Title: The Use of Colloidal Silica Reference Material IRMM-304 for Quality Control in Nanoparticle Sizing by Dynamic Light Scattering and Centrifugal Sedimentation
Citation: Abstracts and proceedings - WCPT62010 p. 4 pp.
Publisher: NuernbergMesse
Publication Year: 2010
JRC N°: JRC56987
URI: http://publications.jrc.ec.europa.eu/repository/handle/JRC56987
Type: Articles in periodicals and books
Abstract: The behaviour of nanoparticles in air or liquids depends on their morphology and size. The ability to accurately measure the particle size is therefore primordial to assess the potential applications and risks associated with nanoparticles. Reference Materials (RMs) can be used to demonstrate reiliability of particle sizing techniques and the comparability of their results. Only few RMs of commercially relevant nanoparticles are available. In response to this, the Institute for Reference Materials and Measurements (IRMM) has produced a nanoparticle RM, IRMM-304, which is primarily intended for quality control, method development and interlaboratory comparisons. IRMM-304 consists tof an aqueous suspension of silica nanoparticles with a nominal diameter of 40 nm. The assigned values have established by dynamic light scattering (frequency and cumulants method) and centrifugal sedimentation. This paper gives examples of how IRMM-304 can be used in daily laboratory practice and quality control.
JRC Directorate:Health, Consumers and Reference Materials

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