First Certified Reference Material for Cystatin C in Human Serum ERM-DA471/IFCC

The IFCC Working Group for standardisation of Cystatin C (WG-SCC) in collaboration with the Institute for Reference Materials and Measurements (IRMM) announces the availability of the new certified reference material ERM-DA471/IFCC. The material was characterised using a pure protein primary reference preparation (PRP) as calibrant. The PRP was prepared from recombinant cystatin C and its concentration determined by dry mass determination. The characterisation of ERM-DA471/IFCC was performed by particle enhanced immune-nephelometry, particle enhanced immuno-turbidimetry, and enzyme amplified single radial ummuno-diffusion. The certified cystatin C mass concentration in ERM-DA471/IFCC is 5.48 mg/L, the expanded uncertainty (k= 2) being 0.15 mg/L

GRUBB Anders;  BLIRUP-JENSEN Soren;  LINDSTROM Veronica;  SCHMIDT Camilla;  ALTHAUS Harald;  ZEGERS Ingrid; 

2010-11-30

WALTER DE GRUYTER & CO

JRC60500

1434-6621,   

https://publications.jrc.ec.europa.eu/repository/handle/JRC60500,   

10.1515/CCLM.2010.318,