Novel and established intestinal cell line models - An indispensable tool in food science and nutrition
The aim of this review is to present the recent developments and examine the future potential of functional cell models as indispensable in vitro tools in current food and nutritional science fields. Cell models provide the platform for preliminary research and contribute in the substantiation of health claims in foods by elucidating the biological plausibility through the involved mechanism of action. Applications include research on bioavailability and adsorption/transport in nutritional or toxicological settings, studies on the allergic effects of food components, host-pathogen gut interactions as well as risk assessment and modelling of potential hazardous substances in the food chain.
LANGERHOLC Tomaz;
MARAGKOUDAKIS Petros-Achillefs;
WOLLGAST Jan;
GRADISNIK Lidija;
CENCIC Avrelija;
2012-01-11
ELSEVIER SCIENCE LONDON
JRC60511
0924-2244,
http://www.sciencedirect.com/science/article/pii/S0924224411000604,
https://publications.jrc.ec.europa.eu/repository/handle/JRC60511,
10.1016/j.tifs.2011.03.010,
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