Nanostructured surfaces presenting chemical or topographical patterns are now being increasingly developed in nanobiotechnology. Major applications are related to cell culture models and biodetection. We show that plasma technologies, in particular the combination plasma polymers deposition and etching, together with colloidal lithography, e-beam lithography and microcontact printing, are essential tools to produce nanostructured surfaces. We show that chemical and topographical patterns can be obtained on different substrates, with dimensions down to some 10 nm. The applications of these nanostructured surfaces in biology and bio-detection are reviewed and the advantages and limitation of the techniques underlined.
ROSSI Francois;
COLPO Pascal;
2011-01-11
IOP Publishing Ltd
JRC60701
1742-6596,
http://iopscience.iop.org/1742-6596/252/1/012001,
https://publications.jrc.ec.europa.eu/repository/handle/JRC60701,
10.1088/1742-6596/252/1/012001,
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