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We show that using asymmetric flow-field-flow fractionation and UV-vis detector it is possible to separate, characterize, and quantify the correct number size distribution of gold nanoparticle (AuNP) mixtures of various sizes in the 5-60 nm range for which simple dynamic light scattering measurements give misleading information. The size of the collected nanoparticles fractions can be determined both in solution and in the solid state, and their surface chemistry characterized by NMR. This method will find widespread applications both in the process of "size purification" after the synthesis of AuNP and in the identification and characterization of gold-based nanomaterials in consumer products.
2011-07-06
ELSEVIER SCIENCE BV
JRC63783
0021-9673,   
https://publications.jrc.ec.europa.eu/repository/handle/JRC63783,   
10.1016/j.chroma.2011.01.017,   
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