Point: Put simply, standardization of Cardiac Troponin I is complicated
The manuscript presents the point of view in favour of standardisation in a point-counterpoint article series in Clinical Chemistry. The article stresses the importance of reference measurement procedures and defining appropriately the analytical target taking the particular biochemistry of troponin I, a very important hart infarction marker, into consideration. The biochemical challenges in troponin I standardisation and the concept followed by the IFCC working group aiming at the establishment of a reference system are described. The conclusion is drawn that standardisation of troponin I is complicated but possible and worth the effort seen the positive impact of a successful standardisation on clinical decision making and patient care.
CHRISTENSON Robert;
BUNK David;
SCHIMMEL Heinz;
TATE Jilian;
2012-06-22
AMER ASSOC CLINICAL CHEMISTRY
JRC66171
0009-9147,
https://publications.jrc.ec.europa.eu/repository/handle/JRC66171,
10.1373/clinchem.2011.166140,
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