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dc.contributor.authorLOCATELLI Ericaen_GB
dc.contributor.authorBROGGI Francescaen_GB
dc.contributor.authorPONTI Jessicaen_GB
dc.contributor.authorMARMORATO Patricken_GB
dc.contributor.authorFRANCHINI Fabioen_GB
dc.contributor.authorLENA Stefanoen_GB
dc.contributor.authorCOMES FRANCHINI Mauroen_GB
dc.date.accessioned2012-07-07T00:00:58Z-
dc.date.available2012-07-06en_GB
dc.date.available2012-07-07T00:00:58Z-
dc.date.created2012-05-15en_GB
dc.date.issued2012en_GB
dc.date.submitted2011-12-01en_GB
dc.identifier.citationADVANCED MATERIALS vol. 1 no. 3 p. 342-347en_GB
dc.identifier.issn0935-9648en_GB
dc.identifier.urihttp://onlinelibrary.wiley.com/doi/10.1002/adhm.201100047/abstracten_GB
dc.identifier.urihttp://publications.jrc.ec.europa.eu/repository/handle/JRC67965-
dc.description.abstractA simple method for the synthesis of lipophilic Ag NPs have been developed. The coated Ag NPs have been entrapped into a FDA-approved and targetable PEG-based polymeric nanoparticles, and this nanocarrier has been conjugated with the peptide chlorotoxin. Uptake experiments have shown a cell-specific recognition of the Ag-1-PNPs-Cltx on U87MG cell lines in comparison to Balb/3T3. The uptake of Ag into the cells was quantified and an interesting cytotoxic effect (IC50 = 45 μM) has been found on glioblastoma cell lines.en_GB
dc.description.sponsorshipJRC.I.4-Nanobiosciencesen_GB
dc.format.mediumPrinteden_GB
dc.languageENGen_GB
dc.publisherWILEY-BLACKWELLen_GB
dc.relation.ispartofseriesJRC67965en_GB
dc.titleLipophilic Silver Nanoparticles and Their Polymeric Entrapment into Targeted-PEG-Based Micelles for the Treatment of Glioblastomaen_GB
dc.typeArticles in periodicals and booksen_GB
dc.identifier.doi10.1002/adhm.201100047en_GB
JRC Directorate:Institute for Health and Consumer Protection Historical Collection

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