Title: Carbon nanotubes: potential medical applications and safety concerns
Authors: AMENTA VALERIAASCHBERGER KARIN
Citation: WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY vol. 7 no. 3 p. 371–386
Publisher: WILEY-BLACKWELL
Publication Year: 2015
JRC N°: JRC86300
ISSN: 1939-5116
URI: http://onlinelibrary.wiley.com/doi/10.1002/wnan.1317/abstract;jsessionid=5BDA30FAFA5AC51D97A6A693C65B2F65.f01t02
http://publications.jrc.ec.europa.eu/repository/handle/JRC86300
DOI: 10.1002/wnan.1317
Type: Articles in periodicals and books
Abstract: Carbon nanotubes (CNTs) have unique atomic structure, as well as outstanding thermal, mechanical and electronic properties, making them extremely attractive materials for several different applications. Many research groups are focusing on biomedical applications of carbon-based nanomaterials, however the application of CNTs to the biomedical field is not developing as fast as in other areas. While CNTs-based products are already being used in textiles, polymer matrices to strengthen materials, sports articles, microelectronics, energy storage, etc., medicinal products and medical devices for in vivo application based on CNTs have not been commercialized yet. However, CNTs for biomedical application, i.e. CNTs conjugated to siRNA for cancer therapy, or CNTs for imaging of colorectal cancer and many other products may enter clinical trials in the next years. Concerns related to the toxicity of CNTs must be overcome in order to have these products commercialized in a near future. This paper reviews emerging biomedical applications of carbon nanotubes, specifically for therapy. It also deals with challenges associated with possible medical applications of CNTs, such as their not fully understood toxicological profile in the human body.
JRC Directorate:Institute for Health and Consumer Protection Historical Collection

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