7-Beryllium-Recoil Labelling of Nanoparticles
Irradiation of nanoparticles (NPs) with light ions such as protons and deuterons has proofed to be a valid tool to produce batches of radiolabelled NPs that can be applied in in-vitro and in-vivo radiotracer studies. A necessary prerequisite is that one of the main constituents of the nanomaterial can undergo a nuclear reaction leading to a radionuclide with adequate physical half-life and emission properties. From this point of view some types of NPs such as silica and alumina cannot be activated by this method as none of the radionuclides that can be produced has suitable properties. This chapter reviews a new recoil radiolabelling techniques developed at IHCP/JRC Ispra which is capable of radiolabelling such NPs with 7-beryllium, an isotope suitable for radiotracing studies ove several weeks or months.
HOLZWARTH Uwe;
GIBSON Peter;
DALMIGLIO Matteo;
KOZEMPEL J.;
2016-04-29
Pan Stanford Publishing
JRC86876
978-981-4669-08-5,
https://www.crcpress.com/Isotopes-in-Nanoparticles-Fundamentals-and-Applications/Llop-GomezVallejo/9789814669085,
https://publications.jrc.ec.europa.eu/repository/handle/JRC86876,
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