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dc.contributor.authorKIENZLER AUDEen_GB
dc.contributor.authorBERGGREN ELISABETen_GB
dc.contributor.authorBESSEMS JOSEPHen_GB
dc.contributor.authorBOPP Stephanieen_GB
dc.contributor.authorVAN DER LINDEN SANDERen_GB
dc.contributor.authorWORTH Andrewen_GB
dc.date.accessioned2017-01-13T01:12:23Z-
dc.date.available2014-11-19en_GB
dc.date.available2017-01-13T01:12:23Z-
dc.date.created2014-11-06en_GB
dc.date.issued2017en_GB
dc.date.submitted2014-06-13en_GB
dc.identifier.isbn978-92-79-64812-0en_GB
dc.identifier.issn1831-9424en_GB
dc.identifier.otherEUR 26675en_GB
dc.identifier.otherOP LB-1A-26675-EN-Nen_GB
dc.identifier.urihttp://publications.jrc.ec.europa.eu/repository/handle/JRC90601-
dc.description.abstractHumans and the environment are continuously exposed to a multitude of substances via different routes of exposure. However, the risk assessment of chemicals for regulatory purposes does not generally take into account the “real life” exposure to multiple substances, but mainly relies on the assessment of individual compounds. This report summarizes the different methodologies that are used to assess the toxic effects of mixtures (Chapter 1). It also provides an overview of current legislation in the EU that deals with the safety assessment of chemicals in different matrices and whether, and if so to what extent, the current legislation addresses the toxicological risk of mixtures (Chapter 2). Relevant Guidance Documents from the EU and other countries (USA, Canada) and international organisations (such as the WHO or the OECD) are also included in the review (Chapter 3).en_GB
dc.description.sponsorshipJRC.I.5-Systems Toxicologyen_GB
dc.format.mediumOnlineen_GB
dc.languageENGen_GB
dc.publisherPublications Office of the European Unionen_GB
dc.relation.ispartofseriesJRC90601en_GB
dc.titleAssessment of Mixtures - Review of Regulatory Requirements and Guidanceen_GB
dc.typeEUR - Scientific and Technical Research Reportsen_GB
dc.identifier.doi10.2788/138523en_GB
JRC Directorate:Institute for Health and Consumer Protection Historical Collection

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