Using α radiation to boost cancer immunity?
Radioimmunotherapy delivers radiation directly to cancer cells by the mean of a tumor specific vector coupled to a radionuclide. Alpha radionuclides are very potent agents to treat disseminated cancer and metastasis. The demonstration that alpha radiation can also induce immunogenic cell death reinforces the interest of their clinical development.
GORIN J;
GUILLOUX Yannick;
MORGENSTERN Alfred;
CHEREL M.;
DAVODEAU F;
GASCHET J;
2014-12-11
LANDES BIOSCIENCE
JRC91112
2162-4011,
http://www.tandfonline.com/doi/abs/10.4161/21624011.2014.954925#.VIm8KhA098E,
https://publications.jrc.ec.europa.eu/repository/handle/JRC91112,
10.4161/21624011.2014.954925,
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