Title: Using α radiation to boost cancer immunity?
Authors: GORIN JGUILLOUX YannickMORGENSTERN AlfredCHEREL M.DAVODEAU FGASCHET J
Citation: ONCOIMMUNOLOGY vol. 3 no. 9 p. e954925
Publisher: LANDES BIOSCIENCE
Publication Year: 2014
JRC N°: JRC91112
ISSN: 2162-4011
URI: http://www.tandfonline.com/doi/abs/10.4161/21624011.2014.954925#.VIm8KhA098E
http://publications.jrc.ec.europa.eu/repository/handle/JRC91112
DOI: 10.4161/21624011.2014.954925
Type: Articles in periodicals and books
Abstract: Radioimmunotherapy delivers radiation directly to cancer cells by the mean of a tumor specific vector coupled to a radionuclide. Alpha radionuclides are very potent agents to treat disseminated cancer and metastasis. The demonstration that alpha radiation can also induce immunogenic cell death reinforces the interest of their clinical development.
JRC Directorate:Nuclear Safety and Security

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