Please use this identifier to cite or link to this item:
|Title:||Radioimmunothérapie alpha Principes et intérêts en immunité antitumorale|
|Authors:||MENAGER J; GORIN J; FICHOU Nolwenn; GOUARD S.; MORGENSTERN Alfred; BRUCHERTSEIFER Frank; DAVODEAU F; KRAEBER BODÉRÉ F; CHEREL M.; GASCHET J; GUILLOUX Yannick|
|Type:||Articles in periodicals and books|
|Abstract:||Alpha-radioimmunotherapy (α-RIT) is a targeted anti-tumor therapy using usually a monoclonal antibody specific for a tumor antigen that is coupled to an α-particle emitter. α-emitters represent an ideal tool to eradicate disseminated tumors or metastasis. Recent data demonstrate that ionizing radiation in addition to its direct cytotoxic ability can also induce an efficient anti-tumor immunity. This suggests that biologic effects on irradiated tissues could be used to potentiate immunotherapy efficacy and open door to development of new therapies combining α-RIT and different types of immunotherapy.|
|JRC Directorate:||Nuclear Safety and Security|
Files in This Item:
There are no files associated with this item.
Items in repository are protected by copyright, with all rights reserved, unless otherwise indicated.