The EURL ECVAM status report provides an update on the progress made in the development, validation and regulatory acceptance of alternative methods and approaches and their dissemination since the last report published in June 2014. It is informing on ongoing research and development activities, validation studies, peer reviews, recommendations, strategies and regulatory/international acceptance of alternative methods and approaches and dissemination activities. R&D activities within large European or International consortia continued in toxicity areas where 3Rs solutions are more difficult to find due to the underlying complexity of the area. On the other hand, toxicity areas where promising non-animal approaches have been developed, their validation and regulatory acceptance/international adoption could be progressed. Particular emphasis was given to the best and most intelligent combination and integration of these different non-animal approaches to ultimately obtain the required information without resorting to animal testing.

ZUANG Valerie;  DESPREZ Bertrand;  VIEGAS BARROSO Joao Filipe;  BELZ Susanne;  BERGGREN Elisabet;  BERNASCONI Camilla;  BESSEMS Joseph;  BOPP Stephanie;  CASATI Silvia;  COECKE Sandra;  CORVI Raffaella;  DUMONT Coralie;  GOULIARMOU Varvara;  GRIESINGER Claudius;  HALDER Maria Elisabeth;  JANUSCH ROI Annett;  KIENZLER Aude;  LANDESMANN Brigitte;  MADIA Federica;  MILCAMPS Anne;  MUNN Sharon;  PRICE Anna;  PRIETO PERAITA Maria Del Pilar;  SCHAEFFER Michael Wilhelm;  TRIEBE Jutta;  WITTWEHR Clemens;  WORTH Andrew;  WHELAN Maurice; 

2015-10-13

Publications Office of the European Union

JRC97811

978-92-79-51989-5 (print),    978-92-79-51990-1,   

1018-5593 (print),    1831-9424 (online),   

EUR 27474,    OP LB-NA-27474-EN-C (print),    OP LB-NA-27474-EN-N (online),   

https://publications.jrc.ec.europa.eu/repository/handle/JRC97811,   

10.2788/38044 (print),    10.2788/62058 (online),