Toxicity of chloroanilines to "Eisenia foetida" was found by a filter paper contact test to range from 2.9 ng/cm2 to 100 ng/cm2. Toxicity increased by a factor two for increasing number of chlorine substituants (from di- to tetra-) in the aniline; that is increasing (kow) and decreasing (S). Little effect of isomer substitution pattern was observed. Correlation coefficients between acute toxicity (LC50) and Kow or S were too weak with r2 = 0.85 and r2 = 0.51, respectively, partly due to the uncertainty of LC50 data and partly due to artificial exposure during filter paper contact test.
MANNONE P.;
1995-03-15
JRC11250
https://publications.jrc.ec.europa.eu/repository/handle/JRC11250,
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