An official website of the European Union How do you know?      
European Commission logo
JRC Publications Repository Menu

Advancing New Approach Methodologies (NAMs) for Tobacco Harm Reduction: Synopsis from the 2021 CORESTA SSPT—NAMs Symposium

cover
New Approach Methodologies (NAMs) are an emerging set of chemical safety assessment tools comprised of in vitro and in silico (computational) methodologies, intended to reduce, refine, or replace (3R) various in vivo animal testing methods traditionally used for risk assessment. A virtual symposium was held during the 2021 CORESTA SSPT conference (titled “Advancing New Alternative Methods for Tobacco Harm Reduction”), with the goals of introducing the concepts and potential application of NAMs in the evaluation of potentially reduced-risk (PRR) tobacco products. At the symposium, experts from regulatory agencies and research organizations shared insights on the status and available tools, strengths, limitations, and opportunities in application of NAMs using case examples from safety assessments of environmental chemicals and tobacco products. The symposium, endorsed by the CORESTA In Vitro Tox Subgroup, Biomarker Subgroup, and NextG Tox Task Force, illustrated the common ground and interest in science-based engagement across the scientific community and stakeholders in support of tobacco regulatory science. Highlights of the symposium are summarized in this paper.
2023-01-31
MDPI
JRC129435
2305-6304 (online),   
https://www.mdpi.com/2305-6304/10/12/760,    https://publications.jrc.ec.europa.eu/repository/handle/JRC129435,   
10.3390/toxics10120760 (online),   
Language Citation
NameCountryCityType
Datasets
IDTitlePublic URL
Dataset collections
IDAcronymTitlePublic URL
Scripts / source codes
DescriptionPublic URL
Additional supporting files
File nameDescriptionFile type 
Show metadata record  Copy citation url to clipboard  Download BibTeX
Items published in the JRC Publications Repository are protected by copyright, with all rights reserved, unless otherwise indicated. Additional information: https://ec.europa.eu/info/legal-notice_en#copyright-notice