Inter-laboratory comparison on the determination of the hydrophobicity index of nanomaterials through an affinity measurement
Hydrophobicity is a physico-chemical property that may influence the fate of nanomaterials in the environment and biological matrices. A method to characterise the hydrophobicity of nanomaterials was developed at the JRC and proposed as an OECD Test Guideline. In this context, the JRC led an Inter-laboratory comparison (ILC) aiming to assess the transferability of the standard operating procedure. The method is based on the measurement of the affinity of nanomaterials to engineered collectors. Nine laboratories participated to this ILC. The variability of the measurements and the reproducibility of the calculation of the Hydrophobicity Index were assessed according to the International Standard ISO 5725-2. Accordingly, with |Z-scores| < 2 for all the participants, the determination of the Hydrophobicity Index was considered satisfactory. The method was adopted by the OECD Working Party of the National Coordinators of the Test Guidelines Programme in April 2023 as Test Guideline 126.
DESMET Cloe;
RONCARI Francesco;
GOTTARDO Stefania;
PONTI Jessica;
RIEGO SINTES Juan;
COLPO Pascal;
VALSESIA Andrea;
2023-06-14
Publications Office of the European Union
JRC133937
978-92-68-04186-4 (online),
1831-9424 (online),
EUR 31542 EN,
OP KJ-NA-31-542-EN-N (online),
https://publications.jrc.ec.europa.eu/repository/handle/JRC133937,
10.2760/486603 (online),
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