Assessment of the relevance and reliability of alternative toxicological methods requires the application of biostatistical methods. This report contains the recommendations of the ECVAM Task Force on Biostatistics for the appropriate use of biometrical methods and for closer collaboration between biostatisticians and experimental toxicologists in the development and validation of alternative methods. The main, objectives of these recommendations are to improve the compatibility of the results obtained from different studies, and to prevent the misinterpretation of statistical analyses. The following points are discussed: the general importance of biostatistics in the development and validation of alternative tests; optimisation of study designs; statistical characterisation and processing of toxicological data; the analysis of relationships which may exist between data obtained from various tests.
HOLZHUETTER Hermann G.;
ARCHER Graeme;
DAMI N.;
SALTELLI Andrea;
SJOSTROM M.;
1997-02-03
JRC14397
https://publications.jrc.ec.europa.eu/repository/handle/JRC14397,
| Name | Country | City | Type |
|---|
This document is only visible at the Commission level.
You are not authorized to publish or distribute it outside the European Commission.
This is a public document. You can share this publication.
Datasets
| ID | Title | Public URL |
|---|
Dataset collections
| ID | Acronym | Title | Public URL |
|---|
Scripts / source codes
| Description | Public URL |
|---|
Additional supporting files
| File name | Description | File type |
|---|