Title: EURL ECVAM Status Report on the Development, Validation and Regulatory Acceptance of Alternative Methods and Approaches (2013-April 2014)
Authors: ZUANG ValerieDESPREZ BERTRANDVIEGAS BARROSO JOAO FILIPEBERGGREN ELISABETBERNASCONI CamillaBESSEMS JOSEPHCASATI SilviaCOECKE SandraCORVI RaffaellaGRIESINGER ClaudiusHALDER MARIA ELISABETHJANUSCH ROI AnnettLANDESMANN BrigitteMADIA FEDERICAMILCAMPS AnneMUNN SHARONPRICE AnnaPRIETO PERAITA Maria Del PilarSCHAEFFER MICHAEL WILHELMWITTWEHR ClemensWORTH AndrewWHELAN Maurice
Publisher: Publications Office of the European Union
Publication Year: 2014
JRC N°: JRC90989
ISBN: 978-92-79-38865-1 (print)
978-92-79-38864-4 (pdf)
ISSN: 1018-5593 (print)
1831-9424 (online)
Other Identifiers: EUR 26702
OPOCE LB-NA-26702-EN-C (print)
OPOCE LB-NA-26702-EN-N (online)
URI: http://publications.jrc.ec.europa.eu/repository/handle/JRC90989
DOI: 10.2788/8638
10.2788/86047
Type: EUR - Scientific and Technical Research Reports
Abstract: The EURL ECVAM status report provides an update on the progress made in the development, validation and regulatory acceptance of alternative methods and approaches since the last report published in April 2013. It is informing on ongoing research and development activities, validation studies, peer reviews, recommendations, strategies and international acceptance of alternative methods and approaches. R&D activities are ongoing for the complex endpoints where the toxicological processes and the mechanistic understanding have not been sufficiently elucidated yet and for which 3Rs solutions are more difficult to find. On the other hand, good progress In the validation and regulatory acceptance is made in areas where non-animal alternative methods have been developed and validated and where the focus lies in an intelligent combination/ integration of the various non-animal approaches.
JRC Directorate:Institute for Health and Consumer Protection Historical Collection

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