This document provides guidance to GMO control laboratories on how to estimate measurement uncertainty (MU) associated with any GMO measurement result.
Competent authorities have a responsibility to decide if a measurement result exceeds the legal threshold. Consequently control laboratories must estimate and report the MU of their measurement results. Quantitative polymerase chain reaction (qPCR) and digital polymerase chain reaction (dPCR) are the methods applied for the enforcement of EU law on GMO labelling.
This document takes into account: current EU legislation, the availability of certified reference materials (CRMs) and validated methods, and the need for control laboratories which conduct measurements for the enforcement of EU legislation to be accredited according to ISO/IEC 17025. Based on these, two approaches for the estimation of MU for PCR measurement results are presented in this guidance document. References to alternative approaches are also provided.
Trapmann, S., Burns, M., Corbisier, P., Gatto, F., Robouch, P., Sowa, S. and Emons, H., Guidance document on Measurement Uncertainty for GMO Testing Laboratories 3rd Edition, EUR 30248 EN, Publications Office of the European Union, Luxembourg, 2020, ISBN 978-92-76-19432-3, doi:10.2760/738565, JRC120898.
2020-06-10
Publications Office of the European Union
JRC120898
978-92-76-19432-3 (online)
1831-9424 (online)
EUR 30248 EN , OP KJ-NA-30248-EN-N (online)
; ROBOUCH Piotr; SOWA Slawomir; EMONS Hendrik 