Non-animal Methods in Science and Regulation

EURL ECVAM Status Report 2022

The 2022 EURL ECVAM Status Report describes research, dissemination and promotion activities undertaken recently by the Joint Research Centre’s EU Reference Laboratory for alternatives to animal testing (EURL ECVAM) to further the uptake and use of non-animal methods and approaches in science and regulation. The principle of the Three Rs, i.e. Replacement, Reduction and Refinement of animal use in basic, applied and translational research, as well as for regulatory testing purposes, is firmly anchored in EU legislation, with complete phasing out of animal procedures being the ultimate goal. This is achievable through a transition to new approach methodologies and models based on innovative non-animal technologies and better understanding of biology and disease. The activities and results described in this report have only been possible through fruitful collaboration with EURL ECVAM’s many committed partners and stakeholders.

ZUANG Valerie; DASKALOPOULOS Evangelos ; BERGGREN Elisabet; BATISTA LEITE Sofia ; BOPP Stephanie ; CARPI Donatella ; CASATI Silvia; CORVI Raffaella; CUSINATO Alberto; DECEUNINCK Pierre; DURA Adelaide; FRANCO Antonio; GASTALDELLO Annalisa ; GRIBALDO Laura; HOLLOWAY Marcelle; KATSANOU Effrosyni; LANGEZAAL Ingrid; MORATH Siegfried; MUNN Sharon; PRIETO PERAITA Maria Del Pilar ; PIERGIOVANNI Monica ; WHELAN Maurice ; WITTWEHR Clemens ; WORTH Andrew ; VIEGAS BARROSO Joao Filipe

2023-03-20

Publications Office of the European Union

JRC132525

978-92-76-61969-7 (online) , 978-92-76-61968-0 (print)

1831-9424 (online) , 1018-5593 (print)

EUR 31395 EN , OP KJ-NA-31-395-EN-N (online) , OP KJ-NA-31-395-EN-C (print)

10.2760/500414 (online) , 10.2760/857724 (print)